Intels X79 platform may seem a little dated by this point, but it in fact remains the best choice for those needing to build the biggest, baddest PCs around especially with Ivy Bridge-E likely 9+ months away. Complementing X79s goals perfectly is ASUS P9X79 PRO, a motherboard that offers a rich feature-set in both hardware and software."
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips