The Shuttle SH87R6 is a great foundation for a small yet powerful system using the latest in hardware. You can combine a Core i7-4770(K), a couple of SSDs and even a mid-range dual-slot graphics card, for example. It's perfect for bringing along to LAN parties, or you can make yourself a powerful yet tiny, portable PC.
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips