Overclocking with the ASUS M5A99FX Pro R2.0 was relatively straightforward. I followed the usual method of disabling any power-saving options, locked in frequencies manually, and set about my way cranking up the speed. To make things move more quickly, after setting the basics in the BIOS, I fired up ASUS AI Suite to start iterating on my settings. After a few rounds through setting and testing I was sitting fat and happy at a very much thermally limited 4715 MHz at 1.43 volts. Any lower on the voltage would yield a failure on core #5 (which was the first one to fail in every single test) and any higher on either the voltage or clocks pushed the CPU into thermal throttling after a few minutes of Prime95. The final settings ended up being 200x23.5, 1.43 volts vcore, and 1.225 volts to the memory controller. All of my testing was done with the H100i cranked up to the unbearable maximum of its two 120mm screamers, but there just wasn`t any more headroom to keep it cool under load; the 8350 is not a cool chip when cranked this high. The last 15 MHz came from the board slightly overclocking the FSB even though I locked it in at 200 MHz."
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