A mini ITX PC Case capable of holding a dual PCI slot graphics card, ATX power supply, full sized optical drive, two 3.5' and two 2.5' drives? If you don't believe it exists then you really need to check the latest PC-Q11 Mini ITX Case by Lian Li.
You do software updates to get the most from favourite programs right? Updating a motherboard BIOS can in a timely manner is also critical. The guide to Flashing a Motherboard BIOS spells out the often complicated steps in plain english. PCSTATS Tips