"There were only two cons that I found overall. The backplate is flush with the PCB on the sides and as such doesn't allow some PCI Express slot latching mechanisms to engage fully and that causes the card to not sit properly in the slot. Secondly, the ability to change the voltage is there but currently does not work and is advertised as a feature. Hopefully soon, such voltage adjustments will be allowed."
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips