"Overclocking the MSI Z68A GD80 is in reality the same as overclocking the MSI P67A GD65. The same tools are used and in the end I came up with a slightly better overclock than I did on the P67A GD65 (by about 80MHz). To get to this level I worked exclusively in the Click BIOS and made adjustments to the CPU core voltage, memory voltage and for the most part, left the balance of the voltages on auto. When I did this though, I found that at the maximum clock speed the CPU would start throttling. By adjusting the "Long Duration power limit" from 95 to 110 I was able to eliminate the throttling. This gave me a good 4.96GHz clock speed that proves stable when the CPU is kept cool enough."
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips