The Hybrid PhysX Mod enables hardware PhysX support for Nvidia GPU, when non-Nvidia GPU is used as a primary display device. This version brings support for Nvidia ForceWare 285 family of drivers and Nvidia PhysX System Software 9.11.0621."
Any major computer upgrade generally requires a full software reinstall too. No so if you heed the advice in the guide to Upgrading a Motherboard without Reinstalling. PCSTATS Tips