As far as reliability goes, the PC Tote was extensively tested with systems up to 50lbs/22.7kg, so you needn't worry too much. The nylon strap itself is said to support 3000lbs, so if your system weight a bit more than 50 you can simply tie the straps after you buckle them together. The standard size adjusts to perimeters from 12-54 inches (137cm). These can also be used on full towers if wrapped around the front.